First Full DNA Sequencing of Unhealthy Genomes Ever Decoded in History
DNA sequencing has changed its course in genetic medicine when two research teams independently decoded the first genomes of unhealthy people who carry genetic diseases ever in history of science. Previously, scientists had sequenced DNA from various groups of healthy people.
Here’s the conclusion of the research:
“First, they realized that genetic diseases did not result from the single mutation of common genes, thus requiring scientists to sequence the entire genome to find the cause of a pathology. Second, they realized that finding a disease would be much easier if the mutations were compared against close relatives, as opposed to the “common genome” developed from the small number of previous full genome donors.”
Source: PopSci
Good news is – not only improve its efficiency in genetic medicine in treating genetic diseases, the cost of DNA sequencing can be lowered over period of time (as the cost of DNA sequencing was far expensive and it cost $500 million ten years ago).
via PopSci & The New York Times (Main source)
Picture courtesy of Michael Stravato for The New York Times showing Dr. James R. Lupski, a medical geneticist with Charcot-Marie-Tooth disease, had his whole “unhealthy” genome decoded.